[HTML][HTML] Hepatoprotective effect of Citrus aurantium L. against APAP-induced liver injury by regulating liver lipid metabolism and apoptosis
Y Shu, D He, W Li, M Wang, S Zhao, L Liu… - … journal of biological …, 2020 - ncbi.nlm.nih.gov
Acetaminophen (APAP) refers to a medication used to manage pain and fever symptoms,
but it always causes liver injury when overdosed. Zhishi, dried young fruit of Citrus
aurantium L., is a famous Citrus herbal medicine in Asian countries which is rich in dietary
phenolic substances. In this study, the mechanism of Zhishi protected against APAP-induced
liver injury was studied more deeply by metabolomic strategy and pharmacological study.
The metabolomics results demonstrated that Zhishi can prevent the APAP-induced liver …
but it always causes liver injury when overdosed. Zhishi, dried young fruit of Citrus
aurantium L., is a famous Citrus herbal medicine in Asian countries which is rich in dietary
phenolic substances. In this study, the mechanism of Zhishi protected against APAP-induced
liver injury was studied more deeply by metabolomic strategy and pharmacological study.
The metabolomics results demonstrated that Zhishi can prevent the APAP-induced liver …
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